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Breakdown Clinically Advanced Digestive Enzyme Matrix

Breakdown: By Genepro Protein, Inc.

What is it?  

A unique blend of digestive enzymes designed specifically to improve gut health, help combat symptoms of lactose and gluten intolerances, improve nutrient uptake, and help boost immune function. 

What are digestive enzymes?

Digestive enzymes are responsible for breaking down the food we eat into molecular building blocks small enough to pass through the small intestine.  These nutrients are then either used for energy or stored for use at a later time. 

Why do I need to supplement with digestive enzymes? 

As we age our bodies get less and less efficient.  There are certain enzymes we stop producing altogether, and some that just lag behind a little.  When this occurs we absorb less of the essential nutrients from our food that our bodies require to function, which very commonly leads to other definices like vitamin D, calcium, magnesium, and others.  

When to take Breakdown?

Breakdown should be taken either during your meals, or directly after.  If you commonly experience bloating, diarrhea, or gas from certain foods, we suggest supplementing with Breakdown during those meals specifically to help reduce some of those discomforts.

Am I lactose intolerant?    

A staggering 68% of the world's population falls somewhere on the lactose intolerance spectrum from moderate to severe.  As infants our bodies produce lactase, a digestive enzyme dedicated to breaking down lactose in the small intestine.  However, as we begin to age our bodies begin to struggle to adequately break down lactose causing symptoms such as diarrhea, gas, and bloating.  Lactose intolerance or malabsorption can be especially common after weight loss surgery creating a need to supplement your diet with a digestive enzyme blend such as BREAKDOWN.3  

PROTEASE 1 & 2:A protease is an enzyme that helps proteolysis: protein catabolism by hydrolysis of peptide bonds. Proteases have evolved multiple times, and different classes of protease can perform the same reaction by completely different catalytic mechanisms. Proteases can be found in Animalia, Plantae, Fungi, Bacteria, Archaea and viruses.


ASPERGILLOPEPSIN: Aspergilloglutamic peptidase, also called aspergillopepsin II is a proteolytic enzyme. The enzyme was previously thought be an aspartic protease, but it was later shown to be a glutamic protease with a catalytic Glu residue at the active site, and was therefore renamed aspergilloglutamic peptidase


AMYLASE:  An amylase is an enzyme that catalyses the hydrolysis of starch into sugars. Amylase is present in the saliva of humans and some other mammals, where it begins the chemical process of digestion. Foods that contain large amounts of starch but little sugar, such as rice and potatoes, may acquire a slightly sweet taste as they are chewed because amylase degrades some of their starch into sugar.

LIPASE: A lipase is an enzyme that catalyzes the hydrolysis of fats. Lipases are a subclass of the esterases. Lipases perform essential roles in digestion, transport and processing of dietary lipids in most, if not all, living organisms. Genes encoding lipases are even present in certain viruses.

CELLULASE: Cellulase is any of several enzymes produced chiefly by fungi, bacteria, and protozoans that catalyze cellulolysis, the decomposition of cellulose and of some related polysaccharides. The name is also used for any naturally occurring mixture or complex of various such enzymes, that act serially or synergistically to decompose cellulosic material.

GLUCOAMYLASE: Glucoamylase (also known as amyloglucosidase or AMG) is an importantdigestive enzyme thathelps us absorb nutrients and create energy from some of the most common plant foods that we eat.

INVERTASE: Invertase is an enzyme that catalyzes the hydrolysis of sucrose into fructose and glucose. Alternative names for invertase include EC, saccharase, glucosucrase, beta-h-fructosidase, beta-fructosidase, invertin, sucrase, maxinvert L 1000, fructosylinvertase, alkaline invertase, acid invertase, and the systematic name: beta-fructofuranosidase. The resulting mixture of fructose and glucose is called inverted sugar syrup. Related to invertases are sucrases. Invertases and sucrases hydrolyze sucrose to give the same mixture of glucose and fructose. Invertases cleave the O-C(fructose) bond, whereas the sucrases cleave the O-C(glucose) bond.

ALPHA-GALACTOSIDASE: Alpha-galactosidase is a glycoside hydrolase enzyme that hydrolyses the terminal alpha-galactosyl moieties from glycolipids and glycoproteins. It is encoded by the GLA gene. Two recombinant forms of alpha-galactosidase are called agalsidase alfa (INN) and agalsidase beta (INN).

BETA-GLUCANASE: Beta-glucanase is anenzyme that has been found to be particularly useful in reducing the coating or biofilm of Candida that can grow in the digestive tract. When an overabundance of beta-glucan is secreted by gut bacteria or candidal cells, there is a build up of biofilms within the organism.

PECTINASE: Pectinase is an enzyme that breaks down pectin, a polysaccharide found in plant cell walls. Commonly referred to as pectic enzymes, they include pectolyase, pectozyme, and polygalacturonase, one of the most studied and widely used commercial pectinases.

XYLANASE: Xylanase (pronounced zy-lan-ase) is a naturally-occurring enzyme that can have beneficial impacts on human health and digestion.[1] Fungi and bacteria produce xylanase, and it's produced by insects, crustaceans like snails, and even seeds.[2] Mammals, including humans, do not produce xylanase, but some of our gut bacteria do. Scientifically speaking, it is an enzyme that breaks down xylan, a type ofhemicellulose, by cleaving the molecule’s beta 1,4 backbone into a simple sugar called xylose. Xylan is the second most common polysaccharide in nature and is a component of plant cell walls.

PHYTASE: Phytase is a phosphatase enzyme that catalyzes, or kickstarts, the hydrolysis of phytic acid, also known as phytate. Phytic acid is a form of indigestible phosphorus that’s present in plant-based foods such as cereal, wheat, andvarious grains. Roughly two-thirds of the phosphorus present in plant foods is bound in the form of phytic phosphate. Through the hydrolysis reaction, phytase liberates phosphorus so that the body can use it.

HEMICELLULOSE: A hemicellulose is a heteropolymer, such as arabinoxylans, present along with cellulose in almost all plant cell walls. While cellulose is crystalline, strong, and resistant to hydrolysis, hemicellulose has a random, amorphous structure with little strength. It is easily hydrolyzed by dilute acid or base as well as a myriad of hemicellulase enzymes.

LACTASE is an enzyme that aids in the digestion of lactose. Lactose is in dairy foods like ice cream, cheese, and milk. This supplement is used to break down lactose and prevent bloating, diarrhea, and gas of lactose intolerance.

BROMELAIN: Bromelain is used for reducing swelling (inflammation), especially of the nose andsinuses, after surgery or injury. It is also used for hay fever, treating a bowel condition that includes swelling and ulcers (ulcerative colitis), removing dead and damaged tissue after a burn (debridement), preventing the collection of water in thelung (pulmonaryedema), relaxing muscles, stimulating musclecontractions, slowing clotting, improving the absorption ofantibiotics, preventingcancer, shortening labor, and helping the body get rid of fat.

PAPAIN: Papain is taken from the fruit of the papaya tree. It is used to make medicine.

Some people take papain by mouth for pain and swelling (inflammation) and to remove extra fluid following trauma and surgery. It is also taken by mouth to help with digestion, to treat parasitic worms, inflammation of the throat and pharynx, shingles (herpes zoster) symptoms, sore muscles, diarrhea, hay fever, runny nose, and a skin condition called psoriasis. Papain is also taken by mouth to treat the side effects of radiation therapy, or it may be used in combination with other therapies to treat tumors. Some people apply papain directly to the skin to treat insect or animal bites, infected wounds, sores, and ulcers

PEPTIDASE: Peptidase, also known as protease or proteolytic is an enzyme with a very important role in the hydrolysis of proteins. Hydrolysis is the process of breaking down bigger molecules into smaller parts, in this case from proteins deriving peptides and even smaller units called amino acids. The role of peptidase is also to help the immune system focus on bacterial or parasitic invasion. Since viruses are parasitic cells covered by a protein film, they are broken down by proteases thus removing any threat to the organism.!